- Novartis obtains rights to develop and commercialize subcutaneous formulations for multiple products utilizing ALT-B4
- Alteogen’s fourth licensing agreement signed this year further accelerating the expansion of the Hybrozyme™ platform
DAEJEON, South Korea, Sept. 2, 2026 /PRNewswire/ — Alteogen Inc. (KOSDAQ: 196170), a leading biopharmaceutical company specializing in platform technologies, announced today that it has entered into an option and license agreement with Novartis for the development and commercialization of subcutaneous (SC) products utilizing ALT-B4 powered by Alteogen’s Hybrozyme™ technology.
Under the terms of the agreement, Novartis will have multiple options to obtain exclusive rights to develop and commercialize subcutaneous formulations for multiple Novartis products using Alteogen’s ALT-B4 (berahyaluronidase alfa).
ALT-B4 (berahyaluronidase alfa) is a proprietary recombinant human hyaluronidase developed using Alteogen’s Hybrozyme™ platform technology. ALT-B4 enables the conversion of biologics typically administered via intravenous (IV) infusion into more convenient and rapid subcutaneous (SC) formulations. By temporarily depolymerizing hyaluronan in the extracellular matrix, ALT-B4 facilitates the rapid and efficient dispersion and absorption of co-administered therapeutics. The agreement demonstrates Novartis’ commitment to innovating new options for patients and enhancing the treatment experience.
If all options are exercised and all milestones are achieved, Alteogen would be eligible to receive up to US$3,223 million, including option exercise fees, development and commercial milestone payments, as well as royalties on net sales of products commercialized under the agreement.
“Novartis is a world-leading pharmaceutical company at the forefront of the global healthcare industry and has evaluated the application of ALT-B4 across multiple modalities for subcutaneous formulation development. This agreement demonstrates the technological strength and commercial value of Alteogen’s Hybrozyme™ platform,” said Tae-Yon Chun, Ph.D., CEO of Alteogen.
About Alteogen
Alteogen Inc. is a South Korea-based biopharmaceutical company that focuses on the development and commercialization of novel biologics such as Antibody-Drug Conjugates (ADCs), biobetters, and biosimilars. Alteogen’s portfolio includes clinical-stage long-acting therapeutic proteins and next-generation ADCs, developed by its proprietary NexP™-fusion and NexMab™ platform technology, respectively. It also developed a proprietary recombinant human hyaluronidase enzyme utilizing Hybrozyme™ technology, which enables the large volume subcutaneous administration of drugs that are typically administered as an IV infusion. The company was founded in 2008 and listed on KOSDAQ (196170.KQ).
Contact
Vivek Shenoy, Ph.D., MBA
Chief Business Officer
Phone: +1 805 570 8998
E-mail: vivek_shenoy@alteogen.com
Siddharth Akolkar, MSc, MBA
Business Development Director
Phone: +1 862 235 8516
E-mail: siddharth_akolkar@alteogen.com
Business Development
E-mail: alliance@alteogen.com
