The Israeli military said it targeted multiple missile and UAV sites in western Iran, including surface-to-surface missile infrastructure, surface-to-air launchers and drone storage facilities, in a statement accompanied by black-and-white footage showing missile launchers exploding.
Shortly after, air raid sirens sounded in parts of Israel.
Loud booms were heard over Jerusalem and Tel Aviv as the Israeli army warned of incoming missiles launched from Iran.
Around 20 minutes later, the army said people could leave protected spaces.
Police said shrapnel fell in Tel Aviv, causing damage but no casualties.
The fire service said its teams were on the way to battle a blaze in the commercial hub.
Despite mounting calls to de-escalate, neither side has backed off from the missile blitz that began on Friday, when Israel launched an unprecedented aerial campaign targeting Iranian nuclear and military facilities.
A new wave of Israeli strikes on Tehran – including a dramatic hit on state television’s headquarters that the broadcaster said killed three people – prompted both sides to activate missile defence systems overnight.
Israel’s army briefly urged citizens to seek shelter, amid growing fears of a regional war.
Pentagon chief Pete Hegseth said the US was deploying “additional capabilities” to the Middle East. The aircraft carrier USS Nimitz left Southeast Asia on Monday, scrapping a planned Vietnam stop, amid reports it was heading to the region.
After calling for talks, Trump issued an extraordinary warning on his Truth Social platform: “Everyone should immediately evacuate Tehran!” He left the G7 in Canada early to return to Washington.
Later, he dismissed reports that he left to broker a ceasefire, lashing out at French President Emmanuel Macron.
“Publicity seeking President Emmanuel Macron… mistakenly said I left the G7… to work on a ‘cease fire,'” Trump posted on Truth Social.
“Wrong! He has no idea why I am now on my way to Washington, but it certainly has nothing to do with a Cease Fire.”
The escalation has derailed nuclear talks and stoked fears of broader conflict. Trump urged Iran to return to the negotiating table.
US Ambassador to Israel Mike Huckabee said a missile strike lightly damaged a building used by the American embassy in Tel Aviv. The State Department warned Americans not to travel to Israel.
At least 24 people have been killed in Israel and hundreds wounded, according to the prime minister’s office.
Iran said on Sunday that Israeli strikes had killed at least 224 people, including military commanders, nuclear scientists, and civilians. It has not issued an updated toll since then.
Israeli Prime Minister Benjamin Netanyahu said Israel was eliminating Iran’s security leadership “one after the other”.
“We are changing the face of the Middle East, and that can lead to radical changes inside Iran itself,” he said.
A senior US official said Trump had intervened to prevent Israel from carrying out an assassination of Iran’s supreme leader, Ayatollah Ali Khamenei.
But Netanyahu did not rule out the possibility when asked about the reports during an interview with ABC News.
“It’s not going to escalate the conflict, it’s going to end the conflict,” he said. (AFP)
